Approach

Own the pathway, not a piece of it

Neuromodulation is split between device makers, imaging centres inside academic institutions, and outpatient clinics treating a narrow band of indications. Avano is structured to hold the whole pathway without concentrating the risk.

Competitive Advantage

Three things nobody else is doing at once

Risk hedged by structure
Separating asset classes inside the fund contains a setback in one from reaching the others, while still allowing vertical integration of the neuromodulation market.
A new indication class
Avano Neuroscience will be the first invasive or non-invasive neuromodulation company to treat peripheral nervous system disorders using central nervous system therapies.
Care and imaging together
Avano Healthcare will be the first clinic to offer full-service neuromodulation care alongside in-house imaging services.
Allocation

Where a €2.2B fund goes

The fund reaches a minimum viable size of €600M and will oversubscribe to €2.2B. Real estate carries the weight; the technology allocations are what make the buildings worth having.

€2B
Real Estate
Clinical facilities across twenty countries of interest, in repurposed commercial space.
€100M
Direct Technology
Non-invasive neuromodulation and brain-computer interface companies, with cross-licensing into new jurisdictions.
€100M
Fund of Funds
Limited partner positions in neurotechnology and artificial intelligence funds, with co-investment alongside partners.
Parameters

Investment Criteria

Stage

Pre-seed, seed, Series A, and fund-of-funds

Sector

Healthcare hardware and AI, real estate, insurance

Technology

Brain-computer interface, deep brain stimulation, non-invasive neuromodulation

Average cheque

€1–5M technology, up to €50M real estate

Geography

North America, MENA, Europe, Australia, Singapore, Japan

Deployment period

Five years, twenty target investments

Investment Strategy

Five allocations, one thesis

Separating asset classes keeps risk contained while the fund integrates vertically across a market that is otherwise split between device makers, imaging centres, and outpatient clinics.

Real Estate
€2B
Direct Technology
€100M
Fund of Funds
€100M
Clinical Infrastructure
In-house
Data and Artificial Intelligence
Licensed

Real Estate

The majority of the fund is deployed into clinical real estate. Across most markets, commercial property remains inexpensive and under-occupied, and its floorplate converts to individual neuromodulation units with minimal renovation.

Bulk purchase and lease of 3-Tesla MRI and stimulation devices drives the cost per site down, which is what makes smaller markets viable rather than merely interesting.

Deployment

Phased across twenty markets

Facilities open in sequence rather than all at once, so each phase is underwritten by what the previous one proved.

Phase I — 2027

United States, Malta, Canada, Estonia

Phase II — 2029

Kuwait, Oman, Saudi Arabia, Australia

Phase III — 2031

France, Norway, Ethiopia, Japan

Phase IV — 2033

Singapore, Chile, United Kingdom, Nigeria

Phase V — 2035

Mexico, South Africa, Korea, Turkey

Fund II

India, Germany, Brazil

European Flagship

Why Malta

A €35M facility investment, thirty clinical specialists, and a ten-person software engineering team.

Rising rates of mental illness, including depression, anxiety, and obsessive-compulsive disorder
Rising rates of inflammatory disease, including irritable bowel syndrome, endometriosis, and rheumatoid arthritis
An ageing population requiring geriatric infrastructure for Parkinson's disease and essential tremor
Additional 3-Tesla MRI capacity contributing to the region's healthcare and digital infrastructure
0

Facility investment, €M

0

Roles created in Malta

Avano will advance the global practice of medicine

We work with limited partners, clinical institutions, and neurotechnology founders building toward the same thing. If that is you, we would like to hear from you.